Acupressure Wristband Relieves Nausea During Migraines (1)
Aside from excruciating pain, nausea and/or vomiting is one of the most bothersome symptoms of migraines. Studies show that it is more common in occurrence than aura among migraineurs of both genders. A good 80% of migraineurs experience degrees of nausea during a migraine attack.
Thankfully, some testing from Berolina Clinic in Lohne, Germany has resulted in an acupressure wristband that subdues symptom of nausea when a migraine episode is underway. Dr. Zoltan Medgyessy, the leading headache physician of the clinic presented in the International Headache Congress 2013 in Boston the efficacy of the wristband. He demonstrated that the wristband applies pressure to point P6, the antiemetic point on the inner wrist providing fast relief from nausea for migraineurs. (2)
The wristband was formed after a study on 41 patients who had averaged 33 days of migraines in the past 3 months and graded a nausea average of 6.2 on a scale of extreme 10. 83% of the nauseous migraineurs experienced a quick mitigation of the symptom to 2.0 out of 10 at approximately 28 minutes from time of wearing the wristband.
According to Dr. Medgyessy, “Acupressure wristbands are drug-free and that is an important advantage in using this therapy for migraine nausea as they have no risks for interaction with migraine drugs or the side effects commonly experienced with antiemetics, such as dizziness or tiredness. There are still many unknowns about migraine, making findings such as these an important stride toward improving the quality of life for those who suffer from the condition.” (3)
- Image credit: Acupressure Wristband from Sea-Band; BaronePharmacy.com; July 2013; http://www.baronepharmacy.com.au/digestive-health/seaband-seaband-acupressure-wristband-childrens-pi-24108.html
- Acupressure Wristband Relieves Migraine Nausea; Medical News Today; Web July 2013; http://www.medicalnewstoday.com/releases/262536.php
- Efficacy of acupressure to relieve migraine nausea presented at International Headache Congress; EurekaAlert.com; Web July 2013; http://www.eurekalert.org/pub_releases/2013-06/rla-eoa061813.php
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OptiNose’s Breath Powered Nasal Delivery Device (1)
Drug delivery technology corporation OptiNose Inc. has presented results of a pivotal phase III TARGET study at the International Headache Congress at Boston comparing both the efficacy and the safety of it’s newly developed technology – the OptiNose Breath Powered nasal delivery device with other drug delivery systems and placebos. The abstracts are to be published in Cephalalgia, the Journal of the International Headache Society
The breath-powered device containing low dose sumatriptan was used to deliver the drug in patients experiencing moderate to severe migraine pain, and then compared to placebo administered via the same route later.
According to Ramy A. Mahmoud, M.D., M.P.H., Chief Operating Officer of OptiNose, “Various data we are presenting today will highlight how this novel delivery technology improves the delivery of medicine to hard-to-reach regions deep in the nasal cavity, how it can produce fast and efficient absorption of medicine into the blood, and how effective treatment with this technology can be. There are nearly 30 million migraine sufferers in the United States and many will be able to benefit from a new low-dose treatment that can rapidly provide effective pain relief with few adverse events.” (2)
Sections discussed in the International Headache Congress 2013 included:
- Efficacy and Safety of a Novel Breath Powered Powder Sumatriptan Intranasal Treatment for Acute Migraine;
- Data from a randomized, single-dose, four-way cross-over study assessing the absorption into the blood of sumatriptan intranasal powder administered using the Breath Powered OptiNose drug delivery device compared to Imitrex® subcutaneous injection, Imitrex nasal spray and Imitrex oral tablets in healthy adult volunteers.
- A review of evidence for human in vivo drug deposition patterns in different regions of the nose with devices intended to provide reliable and efficient drug delivery to upper/posterior nerve structures deep in the nasal cavity.
To know more about the TARGET study, please visit the OptiNose website link given below. (3)
- Image Credit: Nansen Neuroscience Netwrok; Optinose: Novel Nasal Drug Delivery device; Web June 2013; http://www.nansenneuro.net/news/member-news/285-novel-nasal-drug-delivery-device.html
- OptiNose AS to Present Data Highlighting New Migraine Treatment at International Headache Congress; BioSpace.com; Web June 2013; http://www.biospace.com/news_story.aspx?StoryID=301426&full=1
- A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study Evaluating The Efficacy And Safety Of A Single 20 Mg Dose Of Sumatriptan Powder Delivered Intranasally With The Bi-Directional Device In Adults With Acute Migraine With Or Without Aura; TARGET Phase III Study; Optinose.com; Web June 2013; http://www.optinose.com/clinical-trials/target-clinical-trial-for-migraine
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Women Migraineurs Experiencing Aura Are At An Increased Risk Of Suffering All Stroke Types (1)
A research that studied 28,000 women has found that such women as those who experience migraines with aura – either visual or sensational and non-visual are at a significantly increased risk of suffering from all types of strokes (ischemic or hemorrhagic ) as those compared to women who do not experience migraines. The findings of the study are to be presented at the International Headache Congress 2013 at Boston. (2)
Ischemic strokes occur when there is a blockage causing reduced blood supply to any part of the brain leading to brain cell and tissue death. Hemorrhagic stroke occurs when an artery in the brain ruptures and causes bleeding in the brain.
Visual aura in migraineurs is a neurological phenomenon typified by visual aberrations or distortions such as perceiving an image as partly broken or with zigzag lines, experiencing blind spots, having a vision festered with sparks or flashing and shimmering lights, inability to gauge distance or margin between two objects. It could involve seeing of wavy lines and experiencing hallucinations. (3)
Aura a migraineur may suffer from may be non-visual in nature such as experiencing vertigo, numbness of tongue, feeling pins and needles on the palms and face or even experiencing of motor debility.
According to Dr. Tobias Kurth, of Brigham and Women’s Hospital in Boston , “Migraine with aura has been consistently linked with increased risk of ischemic stroke and there is also some evidence that it increases risk of hemorrhagic stroke. In this study we sought to determine the importance of migraine with aura in stroke occurrence relative to other stroke risk factors” (4)
The following observations were made during the study:
Migraineurs With Aura
|Base Year or Year 0
- 430 Ischemic
- 96 Hemorrhagic
- 02 Unknown strokes
It was concluded in the news release that for total, ischemic and hemorrhagic stroke, migraine with aura was a strong relative contributor.
Caution: The data and conclusions of research presented at medical meetings are typically considered preliminary until published in a peer-reviewed medical journal.
- Image Credit: Woman Holding Her Head; Photographer: Marin; FreeDigitalPhotos.net; http://www.freedigitalphotos.net/images/agree-terms.php?id=100173635
- Migraine With Aura May Be Linked to All Stroke Types; Medicinet.com; Web June 2013; http://www.medicinenet.com/script/main/art.asp?articlekey=170823
- Migraines With Aura, Chapter 5, Page 34; Migraines For The Informed Woman by Mamta Singh; ISBN: 978-81-291-1517-1; June 2013; http://www.amazon.com/Migraines-Informed-Woman-Tips-Sufferer/dp/8129115174
- Migraine With Aura May Be Linked to All Stroke Types; WebMD.com; Web June 2013; http://www.webmd.com/migraines-headaches/news/20130626/migraine-with-aura-may-be-linked-to-all-stroke-types
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