Bisphenol A in plastic water bottles and containers found to trigger migraines (1)
Bisphenol A or BPA is a carbon-based synthetic compound and a type of bisphenol that is used in the making of certain plastics and epoxy resins. BPA is known to exhibit hormone mimicking properties when mammals are exposed to it in higher doses but even at lower but sustained exposure to BPA is suspected of causing damage to fetus, infants and the young. Countries of the European Union and Canada have banned the use of BPA in the manufacture of feeding bottles. However, it does go into making plastic containers used for storage in the kitchen and the omnipresent plastic water bottles, plastic microwave trays etc we use every day. It is also found in other products like shower curtains, till receipts etc.
Recently conducted research by University of Kansas on mice showed that such mice as were exposed to BPA every three days exhibited signs of migraines within half an hour of the exposure – becoming almost inactive, keeping away from light or sound, being startled easily and showed signs signalling tenderness in the head region. (2)
Lydia Vermeer, Ph.D., a postdoctoral fellow in Berman’s lab said, “We hypothesized that BPA exposure would activate estrogen receptors, exacerbating migraine symptoms.” The hypothesis that BPA mimics the hormone estrogen was confirmed when the researchers found an influx of estrogen levels signalled by the rat brain in the exposed rats. As per The Mayo Clinic hormone estrogen (as well as progesterone) plays key roles in regulating the menstrual cycle and pregnancy which may affect headache-related chemicals in the brain.
According to the report of the study that was published in the journal Toxicological Sciences, “These results imply that BPA has the ability to amplify symptoms that are used to diagnose the disorder in human patients, suggesting that exposure to BPA would increase both the incidence and prevalence of this disorder.” (3)
As per Dr. Nancy Berman, “This is an entirely new direction for the field of migraine.” (4) The scientists now believe that a change in diet might provide some relief for migraine sufferers, who make more than 68 million visits to physicians’ offices or emergency rooms in the United States each year.
Bisphenol A (BPA) has already been linked to a range of health problems including obesity, infertility and heart attacks.
- Image Credit: Beautiful Woman Drinking Water In Nature; Adamr; freedigitalphotos.net; Web December 2013; http://www.freedigitalphotos.net/images/beautiful-woman-dring-water-in-nature-photo-p219061
- Controversial Bisphenol A in water bottles could be causing migraines; News.com.au; Web December 2013; http://www.news.com.au/lifestyle/health/controversial-bisphenol-a-in-water-bottles-could-be-causing-migraines/story-fneuz9ev-1226775854588
- Chemical commonly found in plastics makes migraines worse, researchers show; Kansas University Medical Center – News; Web December 2013; http://www.kumc.edu/news-listing-page/researchers-show-connection-between-bisphenol-a-and-migraine.html
- To watch the interview with lead researcher Dr. Nancy Berman (PhD: M.I.T., Cambridge, Massachusetts),- Prof. Anatomy and Cell Biology here’s the link on Fox News: http://video.foxnews.com/v/2888723547001/study-finds-possible-link-between-bpa-and-migraine-headaches/?playlist_id=930909749001
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Spoon in a large dollop of ice cream after you enter the house on a warm summer day and you know you are in trouble. The brain freeze will make you repent the haste almost immediately. Same with guzzling down a chilled soda. The sensation on the upper palate almost stops you in your tracks in a very uncomfortable way. Turns out, the mechanism involved in brain freeze is also at play during any migraine episode. (1)
Change in Brain’s Blood Flow Similar in Brain Freeze and a Migraine (2)
It is believed a brain freeze is an experience brought on by other experiences that are interpreted by the brain as traumatic and are often suffered by soldiers who have been close to explosions or have had combat injuries. One link between the brain freeze and the events in the onslaught of a migraine is the way there occurs a change in the blood flow of the brain.
Researchers at the Department of Veterans Affairs New Jersey Health Care System, the National University of Ireland Galway, Harvard Medical School and the the War Related Illness and Injury Study Center of the Veterans Affairs New Jersey Health Care System have observed in the experiments conducted in their study that sudden headache seems to be triggered by an abrupt increase in blood flow in the anterior cerebral artery and disappears when this artery constricts.
In the study the researchers observed 13 healthy adults whose cerebral blood flow was monitored using transcranial Doppler as they sipped ice water with a straw on their upper palate. This was done in order to have an onset of brain freeze. Next their cranial blood flow was noted using the same tool when they were made to sip water of room temperature in the same way. The volunteers were made to signal the onset and the dissipation of the brain freeze. The observations showed that one particular artery, called the anterior cerebral artery, dilated rapidly and flooded the brain with blood in conjunction to when the volunteers felt pain. Soon after this dilation occurred, the same vessel constricted as the volunteers’ pain receded.
As per the study lead Jorge Serrador of Harvard Medical School, “The brain is one of the relatively important organs in the body, and it needs to be working all the time. It’s fairly sensitive to temperature, so vasodilation might be moving warm blood inside tissue to make sure the brain stays warm. But the brain is a closed structure, so the sudden influx of blood could raise pressure and induce pain. The following vasoconstriction may be a way to bring pressure down in the brain before it reaches dangerous levels.” (3)
Serrador has pointed that similar changes in blood flow is noticeable in those who have migraines during a migraine attack or in those with post-traumatic headaches. This provides avenues for pharmaceutical companies to work on a drug that targets on areas based on the finding of this study, thus bringing about a change in the course of migraines and certain headache types.
- Changes in Brain’s Blood Flow Could Cause ‘Brain Freeze’; Science Daily News; April 2012; http://www.sciencedaily.com/releases/2012/04/120422231742.htm
- Image by Victor Habbick; Freedigitalphotos.net; April 2012; http://www.freedigitalphotos.net/images/view_photog.php?photogid=4036
- Changes in Brain’s Blood Flow Could Cause ‘Brain Freeze’; American Physiological Society – Onsite Newsroom; April 2012; http://www.the-aps.org/mm/hp/Audiences/Public-Press/For-the-Press/releases/12/15.html
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