Migraines Peg Risk Of Facial Palsy Significantly

ID-100247674

Migraineurs at Double The Risk Of Developing Facial Paralysis (1)

As per a recent study conducted by a team of scientists working with Taipei Veterans General Hospital in Taiwan and National Yang-Ming University, migraineurs are at almost double the risk than non-migraineurs to develop facial paralysis also known as Bell’s Palsy.

The report of the study was published in the 13th January, 2015 issue of the medical journal Neurology of the American Association of Neurologists. Bell’s Palsy occurs due to the dysfunction of a specific cranial nerve that controls facial muscle movements. Some characteristics involve not being able to blink with the eye on the side the facial nerve is affected. Other signs include development of a facial droop on the affected side. Other things such as smiling, frowning, tear-formation, salivation, flaring nostrils and raising eyebrows may all be affected in Bell’s Palsy.

As per lead researcher and author of the study, Shuu-Jiun Wang, MD, “This is a very new association between migraine and Bell’s palsy. Our study also suggests that these two conditions may share a common underlying link.” (2)

It is assumed that anything between 11 to 40 people in every 100,000 people get Bell’s Palsy due to recurring migraines. In the study two groups of adult population were selected. The total persons under study were 136,704. One group had the migraineurs and the other had the non-migraineurs. The observations of the study continued for a period of 3 years. During that time, 671 people in the migraine group and 365 of the non-migraine group were newly diagnosed with Bell’s palsy. People with migraine were twice as likely to develop Bell’s palsy even after researchers accounted for other factors and medical conditions. (3)

According to Dr. Wang, “Infection, inflammation or heart and vascular problems could be shared causes for these diseases. If a common link is identified and confirmed, more research may lead to better treatments for both conditions.”

SOURCES

  1. Image Credit: Woman Face With Natural Look by Phasinphoto; freedigitalphotos.net; Web January 2015; http://www.freedigitalphotos.net/images/woman-face-with-natural-look-photo-p247674
  2. Migraine May Double Risk Of Facial Paralysis; ScienceDaily.com; Web December 2014; http://www.sciencedaily.com/releases/2014/12/141217171315.htm
  3. Does Migraine Produce Facial Palsy? Neurology; Web January 2015; http://www.neurology.org/content/84/2/108.short

 Copyrights apply to this blog. Please refer copyright permissions.

Defective Nerve Insulation In Migraineurs: Study

ID-100122308

Myelin Sheath & Cellular Elements Over Axons of Nerve Cells Are Patchy Or Missing In Migraineurs (1)

A study conducted by a team of researchers from three different departments at Case Western School of Medicine, clearly exhibits that certain changes at the cellular-level of the nerve structure of migraineurs leads to migraines in many patients. This in turn brings about functional changes of the nerves and further contributes to painful migraine episodes.

The findings of the study were published in the November issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons. You can read the report by clicking on the link below (2)

Myelin is an electricity insulating material that forms a layer/sheath which surrounds the axon of a nerve cell/neuron. The detailed study of miniscule specimens of the trigeminal nerves of migraineurs showed that there were abnormalities in the myelin sheath that served as insulation around nerve fibres in the trigeminal nerves.

Another group of patients that had been evaluated and found eligible and thus had opted for plastic surgery as a route to treat their migraine was also studied. They had all undergone the forehead lift procedure, which involved removal of some muscle and vessel tissue surrounding the cranial nerves.

The nerve fiber samples of all these patients were studied and compared for proteomic analysis. Electron microscopy techniques were used for the process of evaluating the presence and functioning of different proteins in the nerve fiber obtained from the patient’s trigeminal nerves. It was found that migraining patients without the surgery had missing or defective myelin sheaths over their nerve cells compared to those that had opted for the surgery.

As per surgeon Bahman Guyuron, MD, of Case Western Reserve University, “If the insulation becomes cracked or damaged by conditions in the environment, that’s going to affect the cable’s ability to perform its normal function. In a similar way, damage to the myelin sheath may make the nerves more prone to irritation by the dynamic structure surrounding them, such as muscle and blood vessels, potentially triggering migraine attacks.” (3)

Another key observation made was that the placement and organization of cellular elements in the nerve fibers was tight and uniform for the group that undergone surgery to treat migraines whereas the migraining group was found to have a discontinuous and patchy distribution of the cellular elements in their nerve fibers.

This brings to light the criticality of the peripheral nerves in triggering complex events in a migraine attack that eventually involves our central nervous system. Co-authors of this study add, “These findings may also lead to other opportunities to treat patients with migraine headaches non-invasively, or with less invasive procedures that repair the defective myelin around nerves, lending additional protection for the nerves.”

SOURCES

  1. Image Credit: Neurons by Dreams Design; Freedigitialphotos.net; Web November 2014; http://www.freedigitalphotos.net/images/Human_body_g281-Neuron_p122308.html
  2. Excerpt of the study may be read at: Electron Microscopic and Proteomic Comparison of Terminal Branches of the Trigeminal Nerve in Patients with and without Migraine Headaches; Journal of The American Society of Plastic Surgeons; Web November 2014; http://journals.lww.com/plasreconsurg/pages/articleviewer.aspx?year=2014&issue=11000&article=00036&type=abstract
  3. Migraine Linked To Defective ‘Insulation’ Around Nerve Fibers, Suggests Study; Sciencedaily.com; Web November 2014; http://www.sciencedaily.com/releases/2014/11/141103113557.htm

 Copyrights apply to this blog. Please refer copyright permissions.

Happy Deepawali 2014!!

ID-10054566

Wishing All Our Readers A Very Happy, Auspicious, Festive & Prosperous Deepawali!

May You Be Rich Of Friends and Family, Good Health, Ample Time and Life’s Joys:)

Image Credit: Red Candles by think4photop; freedigitalphotos.net; Web October 2014; http://www.freedigitalphotos.net/images/Lighting_g192-Red_Candles_p54566.html

Middle Age Migraineurs At Risk Of Parkinson’s Later

ID-10081435

Studies Show Some Middle-Age Migraineurs Go On To Develop Parkinson’s At Old Age (1)

A recent study conducted at the Uniformed Services University in Bethesda, and published in the medical journal Neurology (of the American Academy of Neurology) , showed that there was a link between migraines and the development of Parkinson’s Disease.

Though severe migraine attacks are considered as disabling as serious illnesses such as dementia, active psychosis or even quadriplegia, it is still the most under-funded and less researched of all neurological diseases in the world.

As per lead author of the study, Ann I. Scher, M.D migraines are the most common brain disorder among both the sexes linked to both cerebrovascular and heart disease. However, the study exhibited that the link between middle-age migraining and Parkinson’s is stronger for women who suffer migraines with aura. She says, “This new possible association is one more reason research is needed to understand, prevent and treat the condition.” (2)

The research involved 5620 persons from Iceland for a period of 25 years. Their ages were between 33 and 65 years at the time when the study began. Of the 5620 persons studied, 1028 had headaches without migraine symptoms, 238 had migraines without aura and 430 experienced migraines with aura. Here are the result highlights:  (3)

  • Migraineurs with aura twice as likely to develop Parkinson’s later than Migraineurs without aura
  • 1% of the persons without headaches developed Parkinson’s later when compared to 2.4% who developed it and had migraines with aura.
  • People with migraine with aura were also around 3.6 times more likely to report at least four of the six symptoms of Parkinson’s, and people with migraine without aura were 2.3 times more likely.
  • Overall rates in absolute terms were as:
        • In people with migraine with aura: 19.7%
        • In people with migraine without aura: 12.6%
        • In people with no headaches at all: 7.5%.

According to Scher, “A dysfunction in the brain messenger dopamine is common to both Parkinson’s and Restless Leg Syndrome (RLS), and has been hypothesized as a possible cause of migraine for many years. Symptoms of migraine such as excessive yawning, nausea and vomiting are thought to be related to dopamine receptor stimulation.  More research should focus on exploring this possible link through genetic studies”

SOURCES

  1. Image Credit: Frustrated Caucasian Woman by Stock Images; Freedigitalphotos.net; Web October 2014; http://www.freedigitalphotos.net/images/Emotions_g96-Frustrated_Caucasian_Woman_p81435.html
  2. Link Found Between Migraine And Parkinson’s; Medical News Today; Web October 2014; http://www.medicalnewstoday.com/articles/282678.php
  3. Migraines In Middle Age, Parkinson’s Risk Later? WebMD.com; Web October 2014; http://www.webmd.com/migraines-headaches/news/20140917/are-migraines-in-middle-age-tied-to-raised-parkinsons-risk-later

Copyrights apply on this blog. Please refer copyright permissions.

Mindfulness Meditation Reduces Suffering In Chronic Migraineurs: Study

Migraine Meditation

Studies Show Meditation Helps Migraineurs (1)

A study conducted by researchers at Wake Forest Baptist Medical Center, Winston-Salem, NC, and Harvard Medical School in Boston, MA, examined 19 adults suffering from chronic migraines in order to find the effects of mindfulness meditation on those experiencing chronic headaches and to test the safety and feasibility of such a practice.

The findings of this study were published online in journal Headache.  Such a test was conducted mainly keeping in mind the hypothesis that stress-trigger in migraines could be addressed mindfulness meditation. As per lead author of the study, Rebecca Erwin Wells, assistant professor of neurology at Wake Forest Baptist, “Stress is a well-known trigger for headaches and research supports the general benefits of mind/body interventions for migraines, but there hasn’t been much research to evaluate specific standardized meditation interventions”. (2)

The study however demonstrated that mindfulness meditation did indeed help alleviate migraine pains and that they were a safe way to reduce the intensity and frequency of the migraines.

Mindfulness-based Stress Reduction or MBSR used yoga, mindfulness meditation and body awareness in a standardized 8-week program on the migraining volunteers. The migraineurs were divided into any of the 2 groups. They were then evaluated on disability, self-efficacy and mindfulness. After this was done, one group received conventional or mainstream migraine management care while the other group took part in the 8-week MBSR program. The MBSR program required the candidates to practice their mindfulness techniques for 45 minutes every day for at least 5 days a week. They were exposed to 1 instruction class every week as well. During this 8-week program all the participants noted how frequent their migraine episodes were, how long they lasted, how intense they were.

The researchers found that the patients who completed the MBSR program tended to have 1.4 fewer headaches per month that were less severe. Not only this, the episodes lasted less longer, were less disabling, the migraineurs felt a better sense of control over the events. Besides this, the program with its techniques proved safe as no adverse side effects were observed during the trial.

However, larger sample sizes and population with varied ethnicity, age groups, gender and socio-economic strata need to be studied for MBSR to be integrated into the mainstream and conventional treatment package for migraineurs.

According to Prof. Wells, “For the approximate 36 million Americans who suffer from migraines, there is a big need for non-pharmaceutical treatment strategies, and doctors and patients should know that MBSR is a safe intervention that could potentially decrease the impact of migraines.” (3)

SOURCES

  1. Image Credit: Woman Doing Yoga On Rock Stock Photo by Adamr; Free Digital Photos; Web September 2014; http://www.freedigitalphotos.net/images/Healthy_Living_g284-Woman_Doing_Yoga_On_Rock_p100414.html
  2. Migraine sufferers may find meditation helps; Medical News Today: Web September 2014; http://www.medicalnewstoday.com/articles/282441.php
  3. Meditation May Mitigate Migraine Misery;Wake Forest Baptist Medical Center – News & Media Resources; Web September 2014; http://www.wakehealth.edu/News-Releases/2014/Meditation_May_Mitigate_Migraine_Misery.htm

Copyrights apply to this blog. Please refer copyright permissions.