Migraineurs Twice More At Risk Of Depression & Suicidal Thoughts

Depression & Migraines

Young Migraineurs Twice Likely To Be Depressed Than Those Healthy (1)

A large-scale study conducted in Canada by researchers from University of Toronto’s Factor-Inwentash Faculty of Social Work on 67,000 persons has now concluded that women under 30 years of age were six times more likely to have migraines co-morbid with depressive states than women older than 65 years of age. The paper which was published in the journal Depression Research and Treatment also stated that the prevalence of depression among those with migraine whether women or men are approximately twice as high as for those without the disease. The findings for depression rates in migraineurs and healthy persons were:

Gender Particular: Depression

Prevalence %

Women With Migraines

12.4

Women Without Migraines

5.7

Men With Migraines

8.4

Men Without Migraines

3.4

 

 The study analysed data which re-validated old truths about gender bias of the disease: that 1 in every 7 women had migraines compared to 1 in every 16 for men.

On similar lines were thoughts on suicide. Those under 30 years of age were four times more likely than those over 65, to consider suicide as a result of debilitating and repetitive migraine episodes. A glance at the findings for seriously contemplating suicide at least once between men and women both with and without migraines:

Gender Particular: Suicidal Thoughts

Prevalence %

Women With Migraines

17.6

Women Without Migraines

9.1

Men With Migraines

15.6

Men Without Migraines

7.9

According to Meghan Schrumm, “We are not sure why younger migraineurs have such a high likelihood of depression and suicidal ideation. It may be that younger people with migraines have not yet managed to find adequate treatment or develop coping mechanisms to minimize pain and the impact of this chronic illness on the rest of their lives. The much lower prevalence of depression and suicidal ideation among older migraineurs suggests a promising area for future research.” (2)

Co-author and researcher Dr. Fuller Thomson states that, “This study draws further attention to the need for routine screening and targeted interventions for depression and suicidality, particularly among the most vulnerable migraineurs: Individuals who are young, unmarried and those with activity limitations.” (3)

SOURCES

  1. Image Credits: Depressed Woman Sitting On Floor ” by David Castillo Dominici; FreeDigitialPhotos.net; Web October 2013; http://www.freedigitalphotos.net/images/agree-terms.php?id=10099322
  2. Migraine sufferers more likely to have depression; Medical News Today; Web October 2013; http://www.medicalnewstoday.com/articles/267610.php
  3. Depression Twice as Likely in Migraine Sufferers; Science Daily News; Web October 2013; http://www.sciencedaily.com/releases/2013/10/131017114231.htm

Copyrights apply on this blog. Please refer copyright permissions.

Advertisements

Implant To Pull The Plug On Migraine Pain

implant to cut off pain

 

Implant That Cuts Off Pain (1)

Another hand-me-down tool in the pain management kit for migraineurs but one that shows promise for the chronic migraineur. Patients who have tried almost all routes to seek relief from popping in painkillers and taking prescription opoids, having botox injected, trying hypnosis and biofeedback as well as other alternative therapies like shiastu and autogenic training but have turned to the doctor dismayed with the results now have hope. There appears to be one last technique/tool that some doctors may suggest to such patients. It is not meant for all migraineurs and is suggested on a case to case basis. It is yet to be approved by the Food and Drug Administration (FDA).

The device was designed for patients of chronic back pain. But now it is holding hope for migraineurs who have tried everything and have no other corner to turn. According to Jenny Bruner who had been dealing with the onslaught of pain for many years, “I went to a neurologist. I was hospitalized. Then they put me on preventative medicines.  We tried acupuncture, even botox. I tried biofeedback, and nothing was working. I didn’t see any hope.  It was so frustrating just living in constant pain. It’s unbearable because you are not able to eat because you are nauseated all the time.” (2) During her years with the neurological disease she tried as many as 62 different medications with little or no help from any.

However, she did in the course come across a management technique involving neuro-stimulation. The treatment was called Transforma and it gave her considerable relief like no other technique or medication had.

The system involved the implantation of tiny leads just below the skin. These sub-cutaneous leads are connected to a battery pack. This battery is implanted in the lower back of the patients. The battery sends electrical pulses of very low voltage to the areas of the brain that process pain and is involved in pain signalling. The beauty of the system is that the migraineur can adjust the voltage strength according to her/his needs or the level of pain being experienced in a migraine episode. The electrical pulses feel like a mild massage.

According to migraine specialist Dr. Jack Chapman, “We are turning on a small electrical signal to the nerve to basically shut off or change that nerves transmission of the pain that people interpret as a headache.” (3) To Bruner, this has been a life-changing treatment. She has retrieved bits of life that she had to let go off.

SOURCES

  1. Image Credit: Asian Girl With Headache; tokyoboy; Freedigitalphotos.net; web October 2013; http://www.freedigitalphotos.net/images/Healthcare_g355-Asian_Girl_With_Headache_p86098.html
  2. Relief for migraine sufferers thanks to small electronic device; ClickOrlando.com; Web October 2013; http://www.clickorlando.com/news/relief-for-migraine-sufferers-thanks-to-small-electronic-device/-/1637132/22282540/-/t3xan8z/-/index.html
  3. New treatment helping people with migraines; WNDU.com; Web October 2013; http://www.wndu.com/news/specialreports/headlines/New-treatment-helping-people-with-migranes-226347731.html

Copyrights apply on this blog. Please refer copyright permissions.

Episode Durations & Number Cutbacks With Diamine Oxidase Pills

swanson-ultra-daosin-30-capsules-300mcg

Diamine Oxidase Supplements May Reduce The Number, Duration, Intensity of Attacks (1)

Researchers have found that taking diamine oxidase supplements significantly reduces the duration of a migraine episode, especially if the migraine has been brought on by food triggers like cheese, caffeine, red wine etc. They have also observed that there exists a mildly indirect relation between to the total number migraine attacks itself in the mid to long run.

Diamine oxidase (DAO) is an amino acid that helps metabolise (break down) histamines released by our bodies. When we eat foods that we are allergic to (because our body cannot handle it’s digestion for any number of reasons specifically lack of appropriate enzymes) then the body perceives the situation as a threat to it’s well being. As a result it begins an immune response. In such as case histamines are released causing the capillary walls to give more access to proteins and white blood cells to engage with the pathogen/trigger/danger. This increase in histamine triggers migraines.

Histamines are also present in certain foods itself that when consumed raise histamine levels of the body and then trigger a migraine. Thus it is obvious that if migraineurs with food or weather triggers are administered an enzyme (such as DAO) that is responsible for the breakdown of histamines, migraine duration and number of attacks would reduce.

According to Joan Izquierdo, MD, from the Faculty of Health Sciences at the International University of Catalonia and the neurology service at Catalonia General Hospital in Barcelona, Spain, who studied men or women between ages 18 to 60 years old with an attack within the previous 6 months, “We diagnosed 137 patients who have a migraine, of who 119 showed deficits of the activity of the enzyme DAO, around 87% of the total patients that we have studied.” (2)

The study did not take into consideration alcoholism, psychiatric disorders, or a diagnosis of any disorder for which a treatment could be used as migraine prevention in the previous 1 month or those who could not consume pork-based products (DAO source).

Normal DAO enzyme activity is considered to be a score of 80. In the study, he found that there was a clear correlation between enzyme score and migraine episodes and intensities. Symptom scores rose progressively as enzyme activity dropped below 80 HDU/mL, with scores 50% to 120% higher in the 30-40 HDU/mL range compared with enzyme activity >80 HDU/mL.

Two groups were made and the control group was administered placebos and the other group was given the DAO supplements. The participant dosage was 2 capsules each after breakfast, lunch and dinner. To understand the pain factor, researchers noted the consumption of triptans by the participants. Those who were on placebos consumed 20% more triptans than those on DAO capsules. The diminished triptan use among patients receiving DAO suggests that the compound may have also reduced the intensity of pain during an attack, the researchers suggest.

Dr. Izquierdo also said, “Diamine oxidase supplementation has shown a significant reduction in crisis duration and a tendency toward a reduction in number of crises,” he said. “The treatment is [safe] because we don’t have any adverse events.” (3)

However, to be sure about the outcome of the research, a larger population needs to be studied cutting across ethnic groups and races. At it’s current stage, it is important thus to educate migraineurs of triggers whether they are of food, hunger, exposure to sun, sleep deprivation or weather and environmental conditions.

SOURCES:

  1. Swanson Ultra Daosin Diamine Oxidase; HealthMonthly.co.uk; Web October 2013; http://www.healthmonthly.co.uk/swanson_ultra_daosin_diamine_oxidase
  2. Migraine Attacks Shortened by Diamine Oxidase Supplements; MedScape.com; Web October 2013; http://www.medscape.com/viewarticle/811920
  3. 90% of Migraines Could Be Prevented with Enzyme; Universitat Internacional de Catalunya; Web October 2013; http://www.uic.es/en/news?id_noti=3273

Copyrights apply to this blog. Please refer copyright permissions.